The construct of fractional-order distinction and integrating is by no agencies new, it can be traced back to the generation of classical concretion itself [ 1-7 ] . In recent old ages, the usage of fractional-order differential equations in mold of biological systems, peculiarly in bacterial growing has attracted the attending of life scientists. The cardinal aim of fractional-order mold is manifested in capturing the growing features in a broader sense, while integer-order differential equations missing this belongings. In the present thesis, our chief aim is to explicate a fresh mold attack and execution of freshly proposed iterative strategies to come close the growing parametric quantities related to the bacterial growing in a inactive every bit good as dynamic environmental conditions. It is deserving adverting that, our proposed iterative strategy revealed good correlativity with experimental informations, when applied on fractional opposite number of the growing theoretical accounts. Furthermore, the fractional-order mold of bacterial chemotaxis phenomenon provides an penetration to come close the growing forms due to chemotactic activity. This attack besides helps the microbiologists to plan better bar schemes to minimise the bacterial disease. For the elaborate survey on bacterial disease and bar schemes, it is suggested to see [ 8-11 ] and mentions in this.
The purpose of this subdivision is to carry on a critical reappraisal of the bing mathematical theoretical accounts for bacterial growing. The usage of mathematical theoretical accounts to gauge the dynamicss of bacterial growing has been deriving a much attending of life scientists form last few decennaries. Recently, the reappraisal surveies by the research workers have highlighted some of advantages and drawbacks of patterning attack [ 12-16 ] . The usual attack in patterning the bacterial growing involves adjustment of the informations to sigmoidal maps such as logistic or Gompertz to quantify some of the growing parametric quantities [ 17-20 ] .
A figure of mathematical theoretical accounts have been reported in literature, in fact several sigmoidal maps ( Logistic, Gompertz, Schnute and Stannard ) were developed to depict bacterial growing. Zwietering et Al. ( 1990 ) and Van Imp et Al. ( 1992 ) conducted a innovator work by supplying a mathematically solid model to obtain growing parametric quantities and besides a elaborate statistical analysis to analyze the efficiency of growing theoretical accounts [ 21-22 ] . The bing theoretical accounts for bacterial growing are reviewed and new mathematical theoretical accounts are presented. There are some chief grounds, why the life scientists are in hunt of the fresh attacks to pattern the bacterial growing. It is found that, bacterial growing is chiefly influenced by the dynamic environmental conditions provided doing it a more complex procedure. In order to get by this complexness, Baranayi et Al. ( 1993 ) developed a comprehensive theoretical account which is capable to capture the dependance of growing parametric quantities on kineticss environmental conditions [ 23 ] . Furthermore, his patterning attempts to explicate the bacterial slowdown stage gained much attending by the research workers in prognostic microbiology. Several research workers in this field developed mathematical theoretical accounts to foretell bacterial growing in different media, Lian Haung et Al. ( 2008 ) is one of them who extended Baranayi’s theoretical account and provided a new passage map to acquire insight about lag stage [ 24-27 ] . The above reappraisal is restricted to the clip dependent bacterial growing. Now, we move on the clip and infinite dependent bacterial growing which is due to the reaction-diffusion and chemotactic activity of bacterial cells which consequences in a assortment of complex spiels like, homocentric circles, sunflower spirals, radial musca volitanss and stripes as depicted in the figures of subsequent subdivisions. The survey of Budrene and Berg et Al. ( 1991 ) reveal that, a bacterial strain E. coli signifiers concentric circles when they are exposed to the foods [ 28 ] . For elaborate survey, we refer the reader to see [ 29-41 ] and mentions in this.
Outline of thesis
There are five chapters in this thesis which are arranged as follows:
Chapters 01 is an debut to the fractional concretion and bacterial growing phenomenon.
Chapter 02 addresses the preliminaries to the mathematical mold, its process and scientific applications. This includes a development of deterministic mathematical theoretical accounts and multinomial estimate for growing parametric quantities. Temperature dependance on bacterial growing and mechanism of Baranayi’s theoretical account is discussed and analyzed with new iterative method proposed by Geijji and found good correlativity with experimental consequences.
Chapter 03 contains experimental consequences which are about the Optical denseness measurings of bacterial samples. Another bacteria numeration technique is used named as feasible cell count and the figure of feasible cells after experiment is mentioned.
Chapter 04 nowadayss an improved iterative method proposed by the writer of this thesis and successfully implemented on fractional order bacterial growing theoretical accounts and compared the efficiency of the method with bing consequences in literature.
In Chapter 05, bacterial chemotaxis theoretical accounts based on reaction-diffusion phenomena ensuing bacterial growing forms has been studied and proposed iterative method employed to come close the bacterial growing.
Numeric simulation for the bacterial growing is done with the assistance of charting public-service corporation of Maple 18.
Preliminary Definitions on Fractional Calculus and Bacterial growing
- . Introduction
Fractional concretion is the survey of differential equations of fractional order which are generalisation of whole number order differential equations and their solutions continuously depend on the solutions of whole number order differential equations
1.2. Preliminaries of Fractional Calculus
Fractional concretion [ 1-5 ] has its beginning in the inquiry of the extension of significance. A well-known illustration is the extension of significance of existent Numberss to complex Numberss, and the extension of significance of factorials of whole numbers to factorials of complex Numberss can be viewed another illustration. In generalised integrating and distinction the inquiry of the extension of significance is: Can the significance of derived functions of built-in orderbe extended to hold significance where N is any irrational, complex or fractional figure?
Leibnitz invented the above notation. Possibly, it was naif drama with symbols that prompted L’Hopital to inquire Leibnitz about the possibility that n be a fraction. “ What ifbe ? ? ” asked L’Hopital. Leibnitz in 1695 replied, “ It will take to a paradox. ” But he added prophetically, “ From this evident paradox, one twenty-four hours utile effects will be drawn. ” In 1697, Leibnitz [ 3-5 ] , mentioning to Wallis ‘s infinite merchandise for, used the notationand stated that differential concretion might hold been used to accomplish the similar consequence. In 1819 derived function of arbitrary order appeared in a published text. The Gallic mathematician S. F. Lacroix [ 3-5 ] published a 700 page text on differential and built-in concretion in which he devoted less than two pages to this subject.
Summary of above treatment
In the letters to J. Wallis and J. Bernoulli ( in 1697 ) Leibniz proposed the possible attack to the procedure of distinction in the context of fractional-order in that sense, for the non-integer values of n the definition takes the undermentioned signifier:
( 1.1 )
( 1.2 )
( 1.3 )
Euler suggested that, this attack is rather utile for other values of N ( negative or non-integer ) . Taking thousand = 1 and n = ? Euler obtained:
( 1.4 )
( 1.5 )
1.2.2. Fractional Derivative of a Basic Power Function
The half derived function of the maptogether with the first derived function. Assume that a mapof the signifier
( 1.6 )
The first derived function is every bit usual
( 1.7 )
Repeating this gives the more general consequence that
( 1.8 )
which, after replacing the factorials with the Gamma map, leads us to
( 1.9 )
Forand, we obtain the half-derivative of the mapas
( 1.10 )
Repeating this procedure outputs
( 1.11 )
which is so the expected consequence i.e. ,
( 1.12 )
From this it is apparent that, merely to existent powers are non constrained with the extension of derived function operator which is defined above. For a general mapand, the complete fractional derived function is
( 1.13 )
For arbitrary, since the gamma map is undefined for statements whose existent portion is a negative whole number. In order to decide this issue, it is suggested to use the fractional derived function after the whole number derived function has been performed. For case,
( 1.14 )
1.2.3. Laplace Transform
We can besides come at the inquiry via the Laplace transform [ 1-5 ] .
( 1.15 )
( 1.16 )
etc. , we assert
( 1.17 )
( 1.18 )
( 1.19 )
as expected. Indeed, given the whirl regulation( and short handingfor lucidity ) we find that
( 1.20 )
( 1.21 )
( 1.22 )
( 1.23 )
which is what Cauchy gave us above. Laplace transforms “ work ” on comparatively few maps, but theyarestill utile for the procedure of work outing differential equations of fractional order.
1.2.4. Laplace Transform on fractional-order derived function
The Laplace transformof Caputo fractional derived function is defined as [ 3-5 ] :
( 1.24 )
1.2.5. Mittag-Leffler map
The Mittag-Leffler map [ 1-5 ] in one parametric quantitywith () is defined by following series representation, valid in the whole complex plane [ 2 ] :
( 1.25 )
1.2.6. Fractional Integrals
188.8.131.52. Riemann–Liouville Fractional Integral
The classical signifier of fractional concretion is given by the Riemann–Liouville built-in, basically what has been described above. The theory for periodic maps, hence including the ‘boundary status ‘ of reiterating after a period, is the Weyl built-in. It is defined on Fourier series, and requires the changeless Fourier coefficient to disappear ( so, applies to maps on the unit circle incorporating to 0 ) . The Riemann-Liouville fractional integral operator [ 1-5 ] of order, of a mapis defined as
( 1.26 )
( 1.27 )
Properties of the operator, we mention merely the followers: Forand
- ( 1.28 )
- ( 1.29 )
- ( 1.30 )
The Riemann-Liouville derived function has certain disadvantages when seeking to pattern real-world phenomena with fractional differential equations.
184.108.40.206. Erdelyi–Kober Integral Operator
The Erdelyi–Kober operator is an built-in operator introduced by Arthur Erdelyi ( 1940 ) and Hermann Kober ( 1940 ) and is given by
( 1.31 )
which generalizes the Riemann fractional integral and the Weyl integral.
220.127.116.11. Hadmard Fractional Integral
TheHadmard fractional integralis introduced by J. Hadmardand is given by the undermentioned expression,
( 1.32 )
Note: A recent generalisation is the followers, which generalizes theRiemann-Liouville fractional integraland theHadmard fractional built-in. It is given by
( 1.33 )
1.2.7. Fractional Derived functions
Not like classical Newtonian derived functions, a fractional derived function is defined via a fractional integral.
18.104.22.168. Riemann–Liouville Fractional Derivative
The Riemann–Liouville fractional derivative [ 1-5 ] of order?for a mapdegree Fahrenheitis defined by
( 1.34 )
Note: the chief disadvantage of Riemann–Liouville fractional derived function is that the fractional derived function of a invariable is non zero. Ifso
( 1.35 )
22.214.171.124. Modified Riemann–Liouville Fractional Derivative
The modified Riemann–Liouville [ 1-5 ] derived function is defined as
( 1.36 )
126.96.36.199. Caputo Fractional Derivative[ 6 ]
There is another option for calculating fractional derived functions ; the Caputo fractional derived function. It was introduced by M. Caputo [ 6 ] in 1967 in his famed paper.In contrast to the Riemann Liouville fractional derived function, when work outing differential equations utilizing Caputo ‘s definition, it is non necessary to specify the fractional order initial conditions. Caputo ‘s definition is illustrated as follows ; the fractional derived function ofin the Caputo sense is defined as
( 1.37 )
188.8.131.52. Jumarie Fractional Derivative
Letbe a uninterrupted map dei¬?ned on, so the Jumarie’s modii¬?ed Riemann-Liouville derivative [ 1-5 ] ofis dei¬?ned as follows
( 1.38 )
wherewith. This fractional order derived function is in fact dei¬?ned through the fractional difference
( 1.39 )
( 1.40 )
( 1.41 )
Let us remember that the Riemann-Liouville derived function is dei¬?ned as follows
( 1.42 )
( 1.43 )
Consequently, the Jumarie’s modii¬?ed Riemann-Liouville derived function can be expressed as follows
( 1.44 )
Note that the Jumarie and the Riemann–Liouville fractional derived functions are equal if. The advantage of Jumarie’s dei¬?nition with regard to the classical dei¬?nition of Riemann–Liouville is that the fractional derived function of a changeless is now zero, as desired.
Table 1.1.Fractional derived function of any order